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In challenging times, such as the COVID-19 pandemic we are currently enduring, it is hard to imagine what life could be like if you were also experiencing a life-threatening condition, on top of grappling with a 'new normal’.
Although fewer than 10 000 Australian women are diagnosed with ovarian cancer each year survival rates are not as high as you might expect.
Unfortunately, most symptoms present late from this disease, and sadly ovarian cancer isn’t detected in this way until it’s too late.
Professor John Hooper and his team, based at the TRI (Translational Research Institute Australia), are striving to help more women overcome this silent disease. Thanks to your generosity, the research team can promote their developments, shed light on ovarian cancer and fund future research.
The team recently received accolade from ANZCOG, the peak national gynaecological cancer clinical trials organisation for Australia and New Zealand. Thanks to this, the team can now move to clinical trial phase, which aims to test the effectiveness of a low-dose of the drug 2-deoxy-D-glucose to understand if “modulation of metabolism can improve the effectiveness of chemotherapy for clear cell ovarian cancer."
Professor Hooper has successfully completed the first part of this study, in collaboration with researchers from the Queensland University of Technology (QUT) and the Mayo Clinic in the United States of America.
“Ovarian clear cell carcinoma is a type of ovarian cancer which is associated with poor prognosis and resistance to chemotherapy,” he said.
“Our pre-clinical work used cells taken from patient tumours, so we were very encouraged that we could use such a low dose of 2-deoxy-D-glucose to overcome the chemotherapy resistance and stop tumour growth.”
Professor Hooper and the team are hoping to begin trialling this treatment with patients within the next 12 months.
Your support means the world to women suffering from ovarian cancer, and makes all the difference to the work of researchers like Professor John Hooper.
Ovarian cancer could affect your grandmother, mother, aunt, cousin, sister, or even yourself. Please give what you can during this time of crisis—where it’s clear medical research is as vital as ever.
Find out more about the team’s recent accolade from ANZGOG.